Integrity of mitochondrial membrane potential reflects human sperm quality
نویسندگان
چکیده
منابع مشابه
Mitochondrial membrane potential disruption pattern in human sperm.
BACKGROUND Loss of mitochondrial membrane potential (DeltaPsi(m)) in spermatozoa is correlated with high levels of reactive oxygen species in semen, abnormal spermiogram parameters, and low success rates of IVF. In somatic cells, the loss of DeltaPsi(m) is primarily associated with several mechanisms of cell death, mainly the activation of caspases. The impact of mitochondrial dysfunction on sp...
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Objective(s): Increased levels of nitric oxide (NO) in the testicular veins of people suffering from varicocele have already been reported. However, the role of NO-synthase (NOS) isozymes and their inhibitors have not been extensively studied. We aimed to evaluate the inhibitory effects of aminoguanidine (AG), on sperm motility, vitality, and mitochondrial membrane potential (MMP) in varicoceli...
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متن کاملthe effect of aminoguanidine on sperm motility and mitochondrial membrane potential in varicocelized rats
objective(s): increased levels of nitric oxide (no) in the testicular veins of people suffering from varicocele have already been reported. however, the role of no-synthase (nos) isozymes and their inhibitors have not been extensively studied. we aimed to evaluate the inhibitory effects of aminoguanidine (ag), on sperm motility, vitality, and mitochondrial membrane potential (mmp) in varicoceli...
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ژورنال
عنوان ژورنال: Andrologia
سال: 2009
ISSN: 0303-4569,1439-0272
DOI: 10.1111/j.1439-0272.2008.00878.x